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Clinical Trials

There is currently no cure for any type of arthritis. However, there are many effective treatments. Through much research and clinical trials. Before any drug makes it to market it goes through a series of clinical trials. In this section you will learn about clinical trials and how you can participate in one.

Find out more about clinical trials.

What is a Clinical Trial?

Types of Trials

Why should I enter a Clinical Trial?

How do I Participate in a Clinical Trial?

Current Clinical trials

What is a Clinical Trial?

A clinical trial is a research study conducted with patients who have been diagnosed
with major illness and generally involves testing of new treatments or finding ways of improving existing treatments. Clinical trials are conducted all over the world in
most large hospitals in an attempt to improve treatment for many diseases.

The main objective of a clinical trial is to compare two or more groups of subjects,
using two or more treatment options to determine the effectiveness of a proposed
drug or biological treatment.

Clinical trials are carefully and ethically designed to allow truthful and precise
collection and analysis of information to find out more about a disease.
Such trials help discover whether a promising new treatment is safe and effective,
as well as giving a better understanding of the current standard treatment,
in the hope of improving the side effects experienced by many patients.

Types of Trials

Clinical trials are conducted in four phases before they can be considered for
registration and use.

Phase I trials involve a small number of patients and are designed to test the
safety and dosage of a new drug and to evaluate side effects of various
dosage levels.

Phase II trials involve larger numbers of patients and test the effectiveness
of a treatment given in a particular dose.

Phase III trials are full-scale controlled examinations of new drugs or
treatments and are designed to more fully explore the potential benefits and
risks of the treatment under study. Often, the standard or current treatment is
compared to a newer and potentially better treatment. This trial is a randomised
trial, meaning the treatment is chosen at random- neither the patient nor the
doctor can decide which treatment the patient will receive. This ensures an equal
number of patients are allocated to each treatment and removes any bias the
doctor or patient may have to one treatment or another.

Phase IV trials allow pharmaceutical companies to monitor any adverse side
effects on a larger scale than Phase III studies and help clarify other uses for
the drugs, for example, treatment of another disease.

Why should I enter a Clinical Trial?

Patients take part in clinical trials for many reasons, usually with the hope of direct treatment benefits for themselves. This might include a greater chance of a cure, a longer time to live or better quality of life. Sometimes patients want to contribute to research that will help future sufferers of the disease.

Patients who participate in clinical trials, in which improved results are seen, have the first chance to benefit from these improved treatments.

How do I participate in a Clinical Trial?

Before you consent to participate in a clinical trial, you will be given an information sheet, which contains all the information about the trial, including the risks and
benefits. With any form of treatment being assessed in a clinical trial, side effects
can be experienced and this is always balanced against the benefits of treatment.
You will also be given the opportunity to discuss the trial with your treating doctor,
who will be able to answer any questions.

If you agree to participate you will be asked to sign a consent form, stating that
you have read and understood the purpose of the trial and the risks and benefits
attached to it. You are free to withdraw from the trial at any time. All the ethical
and legal codes that apply to medical practice are carefully followed in clinical trials.

Current Clinical Trials Report

A core focus of the orthosports is clinical trial involvement. There are a number of trials that orthosports are currently actively involved in; Current projects coming soon,

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